Strumazol
Strumazol Brand names, Strumazol Analogs
- Basolan
- Danantizol
- Favistan
- Frentirox
- Mercaptazole
- Mercasolyl
- Mercazole
- Mercazolyl
- Merkastan
- Merkazolil
- Metazolo
- Methamazole
- Methiamazole
- Methimazol
- Methylmercaptoimidazole
- Metizol
- Metothyrin
- Metothyrine
- Metotirin
- Propyl-Thyracil
- Strumazol
- Strumazole
- Tapazole
- Tapuzole
- Thacapzol
- Thiamazol
- Thiamazole
- Thimazole
- Thycapsol
- Thycapzol
- Thymidazol
- Thymidazole
- USAF EL-30
Strumazol Brand Names Mixture
- No information avaliable
Strumazol Chemical_Formula
C4H6N2S
Strumazol RX_link
http://www.rxlist.com/cgi/generic3/methim.htm
Strumazol fda sheet
Strumazol msds (material safety sheet)
Strumazol Synthesis Reference
No information avaliable
Strumazol Molecular Weight
114.17 g/mol
Strumazol Melting Point
146 oC
Strumazol H2O Solubility
275 g/L
Strumazol State
Solid
Strumazol LogP
-0.34
Strumazol Dosage Forms
Tablet (5 or 10 mg)
Strumazol Indication
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Strumazol Pharmacology
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Strumazol Absorption
Rapid with an oral bioavailability of 93%.
Strumazol side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Strumazol Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Strumazol Organisms Affected
Humans and other mammals
