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Thycapzol Brand names, Thycapzol Analogs

Thycapzol Brand Names Mixture

  • No information avaliable

Thycapzol Chemical_Formula

C4H6N2S

Thycapzol RX_link

http://www.rxlist.com/cgi/generic3/methim.htm

Thycapzol fda sheet

Thycapzol msds (material safety sheet)

Thycapzol MSDS

Thycapzol Synthesis Reference

No information avaliable

Thycapzol Molecular Weight

114.17 g/mol

Thycapzol Melting Point

146 oC

Thycapzol H2O Solubility

275 g/L

Thycapzol State

Solid

Thycapzol LogP

-0.34

Thycapzol Dosage Forms

Tablet (5 or 10 mg)

Thycapzol Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Thycapzol Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Thycapzol Absorption

Rapid with an oral bioavailability of 93%.

Thycapzol side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Thycapzol Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Thycapzol Organisms Affected

Humans and other mammals