Thycapzol
Thycapzol Brand names, Thycapzol Analogs
- Basolan
- Danantizol
- Favistan
- Frentirox
- Mercaptazole
- Mercasolyl
- Mercazole
- Mercazolyl
- Merkastan
- Merkazolil
- Metazolo
- Methamazole
- Methiamazole
- Methimazol
- Methylmercaptoimidazole
- Metizol
- Metothyrin
- Metothyrine
- Metotirin
- Propyl-Thyracil
- Strumazol
- Strumazole
- Tapazole
- Tapuzole
- Thacapzol
- Thiamazol
- Thiamazole
- Thimazole
- Thycapsol
- Thycapzol
- Thymidazol
- Thymidazole
- USAF EL-30
Thycapzol Brand Names Mixture
- No information avaliable
Thycapzol Chemical_Formula
C4H6N2S
Thycapzol RX_link
http://www.rxlist.com/cgi/generic3/methim.htm
Thycapzol fda sheet
Thycapzol msds (material safety sheet)
Thycapzol Synthesis Reference
No information avaliable
Thycapzol Molecular Weight
114.17 g/mol
Thycapzol Melting Point
146 oC
Thycapzol H2O Solubility
275 g/L
Thycapzol State
Solid
Thycapzol LogP
-0.34
Thycapzol Dosage Forms
Tablet (5 or 10 mg)
Thycapzol Indication
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Thycapzol Pharmacology
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Thycapzol Absorption
Rapid with an oral bioavailability of 93%.
Thycapzol side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Thycapzol Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Thycapzol Organisms Affected
Humans and other mammals
