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Tapuzole Brand names, Tapuzole Analogs

Tapuzole Brand Names Mixture

  • No information avaliable

Tapuzole Chemical_Formula


Tapuzole RX_link


Tapuzole fda sheet

Tapuzole msds (material safety sheet)

Tapuzole MSDS

Tapuzole Synthesis Reference

No information avaliable

Tapuzole Molecular Weight

114.17 g/mol

Tapuzole Melting Point

146 oC

Tapuzole H2O Solubility

275 g/L

Tapuzole State


Tapuzole LogP


Tapuzole Dosage Forms

Tablet (5 or 10 mg)

Tapuzole Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Tapuzole Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Tapuzole Absorption

Rapid with an oral bioavailability of 93%.

Tapuzole side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Tapuzole Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Tapuzole Organisms Affected

Humans and other mammals