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Mercazole Brand names, Mercazole Analogs

Mercazole Brand Names Mixture

  • No information avaliable

Mercazole Chemical_Formula


Mercazole RX_link

Mercazole fda sheet

Mercazole msds (material safety sheet)

Mercazole MSDS

Mercazole Synthesis Reference

No information avaliable

Mercazole Molecular Weight

114.17 g/mol

Mercazole Melting Point

146 oC

Mercazole H2O Solubility

275 g/L

Mercazole State


Mercazole LogP


Mercazole Dosage Forms

Tablet (5 or 10 mg)

Mercazole Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Mercazole Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Mercazole Absorption

Rapid with an oral bioavailability of 93%.

Mercazole side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Mercazole Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Mercazole Organisms Affected

Humans and other mammals