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Mercaptazole Brand names, Mercaptazole Analogs

Mercaptazole Brand Names Mixture

  • No information avaliable

Mercaptazole Chemical_Formula


Mercaptazole RX_link

Mercaptazole fda sheet

Mercaptazole msds (material safety sheet)

Mercaptazole MSDS

Mercaptazole Synthesis Reference

No information avaliable

Mercaptazole Molecular Weight

114.17 g/mol

Mercaptazole Melting Point

146 oC

Mercaptazole H2O Solubility

275 g/L

Mercaptazole State


Mercaptazole LogP


Mercaptazole Dosage Forms

Tablet (5 or 10 mg)

Mercaptazole Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Mercaptazole Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Mercaptazole Absorption

Rapid with an oral bioavailability of 93%.

Mercaptazole side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Mercaptazole Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Mercaptazole Organisms Affected

Humans and other mammals