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THA Brand names, THA Analogs

THA Brand Names Mixture

  • No information avaliable

THA Chemical_Formula


THA RX_link

THA fda sheet

THA msds (material safety sheet)


THA Synthesis Reference

No information avaliable

THA Molecular Weight

114.17 g/mol

THA Melting Point

146 oC

THA H2O Solubility

275 g/L

THA State




THA Dosage Forms

Tablet (5 or 10 mg)

THA Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

THA Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

THA Absorption

Rapid with an oral bioavailability of 93%.

THA side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

THA Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

THA Organisms Affected

Humans and other mammals