Tioconazole
Brand names,
Tioconazole
Analogs
Tioconazole
Brand Names Mixture
Tioconazole
Chemical_Formula
C16H13Cl3N2OS
Tioconazole
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Tioconazole
fda sheet
Tioconazole
msds (material safety sheet)
Tioconazole
Synthesis Reference
No information avaliable
Tioconazole
Molecular Weight
387.711 g/mol
Tioconazole
Melting Point
No information avaliable
Tioconazole
H2O Solubility
No information avaliable
Tioconazole
State
Solid
Tioconazole
LogP
4.971
Tioconazole
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Tioconazole
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Tioconazole
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Tioconazole
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Tioconazole
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Tioconazole
Patient Information
Tioconazole
Organisms Affected
Yeast and other fungi