Calmore
Brand names,
Calmore
Analogs
Calmore
Brand Names Mixture
Calmore
Chemical_Formula
C16H13Cl3N2OS
Calmore
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Calmore
fda sheet
Calmore
msds (material safety sheet)
Calmore
Synthesis Reference
No information avaliable
Calmore
Molecular Weight
387.711 g/mol
Calmore
Melting Point
No information avaliable
Calmore
H2O Solubility
No information avaliable
Calmore
State
Solid
Calmore
LogP
4.971
Calmore
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Calmore
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Calmore
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Calmore
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Calmore
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Calmore
Patient Information
Calmore
Organisms Affected
Yeast and other fungi