Sedoval
Brand names,
Sedoval
Analogs
Sedoval
Brand Names Mixture
Sedoval
Chemical_Formula
C16H13Cl3N2OS
Sedoval
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Sedoval
fda sheet
Sedoval
msds (material safety sheet)
Sedoval
Synthesis Reference
No information avaliable
Sedoval
Molecular Weight
387.711 g/mol
Sedoval
Melting Point
No information avaliable
Sedoval
H2O Solubility
No information avaliable
Sedoval
State
Solid
Sedoval
LogP
4.971
Sedoval
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Sedoval
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Sedoval
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Sedoval
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Sedoval
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Sedoval
Patient Information
Sedoval
Organisms Affected
Yeast and other fungi