Shinnibrol
Brand names,
Shinnibrol
Analogs
Shinnibrol
Brand Names Mixture
Shinnibrol
Chemical_Formula
C16H13Cl3N2OS
Shinnibrol
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Shinnibrol
fda sheet
Shinnibrol
msds (material safety sheet)
Shinnibrol
Synthesis Reference
No information avaliable
Shinnibrol
Molecular Weight
387.711 g/mol
Shinnibrol
Melting Point
No information avaliable
Shinnibrol
H2O Solubility
No information avaliable
Shinnibrol
State
Solid
Shinnibrol
LogP
4.971
Shinnibrol
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Shinnibrol
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Shinnibrol
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Shinnibrol
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Shinnibrol
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Shinnibrol
Patient Information
Shinnibrol
Organisms Affected
Yeast and other fungi