Sedimide
Brand names,
Sedimide
Analogs
Sedimide
Brand Names Mixture
Sedimide
Chemical_Formula
C16H13Cl3N2OS
Sedimide
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Sedimide
fda sheet
Sedimide
msds (material safety sheet)
Sedimide
Synthesis Reference
No information avaliable
Sedimide
Molecular Weight
387.711 g/mol
Sedimide
Melting Point
No information avaliable
Sedimide
H2O Solubility
No information avaliable
Sedimide
State
Solid
Sedimide
LogP
4.971
Sedimide
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Sedimide
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Sedimide
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Sedimide
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Sedimide
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Sedimide
Patient Information
Sedimide
Organisms Affected
Yeast and other fungi