Sedisperil
Brand names,
Sedisperil
Analogs
Sedisperil
Brand Names Mixture
Sedisperil
Chemical_Formula
C16H13Cl3N2OS
Sedisperil
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Sedisperil
fda sheet
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msds (material safety sheet)
Sedisperil
Synthesis Reference
No information avaliable
Sedisperil
Molecular Weight
387.711 g/mol
Sedisperil
Melting Point
No information avaliable
Sedisperil
H2O Solubility
No information avaliable
Sedisperil
State
Solid
Sedisperil
LogP
4.971
Sedisperil
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Sedisperil
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Sedisperil
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Sedisperil
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Sedisperil
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Sedisperil
Patient Information
Sedisperil
Organisms Affected
Yeast and other fungi