Valgis
Brand names,
Valgis
Analogs
Valgis
Brand Names Mixture
Valgis
Chemical_Formula
C16H13Cl3N2OS
Valgis
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Valgis
fda sheet
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msds (material safety sheet)
Valgis
Synthesis Reference
No information avaliable
Valgis
Molecular Weight
387.711 g/mol
Valgis
Melting Point
No information avaliable
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H2O Solubility
No information avaliable
Valgis
State
Solid
Valgis
LogP
4.971
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Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
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Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Valgis
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Valgis
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Valgis
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Valgis
Patient Information
Valgis
Organisms Affected
Yeast and other fungi