Talismol
Brand names,
Talismol
Analogs
Talismol
Brand Names Mixture
Talismol
Chemical_Formula
C16H13Cl3N2OS
Talismol
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Talismol
fda sheet
Talismol
msds (material safety sheet)
Talismol
Synthesis Reference
No information avaliable
Talismol
Molecular Weight
387.711 g/mol
Talismol
Melting Point
No information avaliable
Talismol
H2O Solubility
No information avaliable
Talismol
State
Solid
Talismol
LogP
4.971
Talismol
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Talismol
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Talismol
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Talismol
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Talismol
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Talismol
Patient Information
Talismol
Organisms Affected
Yeast and other fungi