alpha-phthalimidoglutarimide
Brand names,
alpha-phthalimidoglutarimide
Analogs
alpha-phthalimidoglutarimide
Brand Names Mixture
alpha-phthalimidoglutarimide
Chemical_Formula
C16H13Cl3N2OS
alpha-phthalimidoglutarimide
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
alpha-phthalimidoglutarimide
fda sheet
alpha-phthalimidoglutarimide
msds (material safety sheet)
alpha-phthalimidoglutarimide
Synthesis Reference
No information avaliable
alpha-phthalimidoglutarimide
Molecular Weight
387.711 g/mol
alpha-phthalimidoglutarimide
Melting Point
No information avaliable
alpha-phthalimidoglutarimide
H2O Solubility
No information avaliable
alpha-phthalimidoglutarimide
State
Solid
alpha-phthalimidoglutarimide
LogP
4.971
alpha-phthalimidoglutarimide
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
alpha-phthalimidoglutarimide
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
alpha-phthalimidoglutarimide
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
alpha-phthalimidoglutarimide
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
alpha-phthalimidoglutarimide
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
alpha-phthalimidoglutarimide
Patient Information
alpha-phthalimidoglutarimide
Organisms Affected
Yeast and other fungi