Asmadion
Brand names,
Asmadion
Analogs
Asmadion
Brand Names Mixture
Asmadion
Chemical_Formula
C16H13Cl3N2OS
Asmadion
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Asmadion
fda sheet
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msds (material safety sheet)
Asmadion
Synthesis Reference
No information avaliable
Asmadion
Molecular Weight
387.711 g/mol
Asmadion
Melting Point
No information avaliable
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H2O Solubility
No information avaliable
Asmadion
State
Solid
Asmadion
LogP
4.971
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Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
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Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Asmadion
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Asmadion
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Asmadion
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Asmadion
Patient Information
Asmadion
Organisms Affected
Yeast and other fungi