Glupan
Brand names,
Glupan
Analogs
Glupan
Brand Names Mixture
Glupan
Chemical_Formula
C16H13Cl3N2OS
Glupan
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Glupan
fda sheet
Glupan
msds (material safety sheet)
Glupan
Synthesis Reference
No information avaliable
Glupan
Molecular Weight
387.711 g/mol
Glupan
Melting Point
No information avaliable
Glupan
H2O Solubility
No information avaliable
Glupan
State
Solid
Glupan
LogP
4.971
Glupan
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Glupan
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Glupan
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Glupan
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Glupan
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Glupan
Patient Information
Glupan
Organisms Affected
Yeast and other fungi