Ectiluran
Brand names,
Ectiluran
Analogs
Ectiluran
Brand Names Mixture
Ectiluran
Chemical_Formula
C16H13Cl3N2OS
Ectiluran
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Ectiluran
fda sheet
Ectiluran
msds (material safety sheet)
Ectiluran
Synthesis Reference
No information avaliable
Ectiluran
Molecular Weight
387.711 g/mol
Ectiluran
Melting Point
No information avaliable
Ectiluran
H2O Solubility
No information avaliable
Ectiluran
State
Solid
Ectiluran
LogP
4.971
Ectiluran
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Ectiluran
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Ectiluran
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Ectiluran
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Ectiluran
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Ectiluran
Patient Information
Ectiluran
Organisms Affected
Yeast and other fungi