Kevadon
Brand names,
Kevadon
Analogs
Kevadon
Brand Names Mixture
Kevadon
Chemical_Formula
C16H13Cl3N2OS
Kevadon
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Kevadon
fda sheet
Kevadon
msds (material safety sheet)
Kevadon
Synthesis Reference
No information avaliable
Kevadon
Molecular Weight
387.711 g/mol
Kevadon
Melting Point
No information avaliable
Kevadon
H2O Solubility
No information avaliable
Kevadon
State
Solid
Kevadon
LogP
4.971
Kevadon
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Kevadon
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Kevadon
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Kevadon
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Kevadon
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Kevadon
Patient Information
Kevadon
Organisms Affected
Yeast and other fungi