Telargan
Brand names,
Telargan
Analogs
Telargan
Brand Names Mixture
Telargan
Chemical_Formula
C16H13Cl3N2OS
Telargan
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Telargan
fda sheet
Telargan
msds (material safety sheet)
Telargan
Synthesis Reference
No information avaliable
Telargan
Molecular Weight
387.711 g/mol
Telargan
Melting Point
No information avaliable
Telargan
H2O Solubility
No information avaliable
Telargan
State
Solid
Telargan
LogP
4.971
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Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Telargan
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Telargan
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Telargan
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Telargan
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Telargan
Patient Information
Telargan
Organisms Affected
Yeast and other fungi