Softenil
Brand names,
Softenil
Analogs
Softenil
Brand Names Mixture
Softenil
Chemical_Formula
C16H13Cl3N2OS
Softenil
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Softenil
fda sheet
Softenil
msds (material safety sheet)
Softenil
Synthesis Reference
No information avaliable
Softenil
Molecular Weight
387.711 g/mol
Softenil
Melting Point
No information avaliable
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H2O Solubility
No information avaliable
Softenil
State
Solid
Softenil
LogP
4.971
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Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Softenil
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Softenil
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Softenil
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Softenil
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
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Patient Information
Softenil
Organisms Affected
Yeast and other fungi