Asmaval
Brand names,
Asmaval
Analogs
Asmaval
Brand Names Mixture
Asmaval
Chemical_Formula
C16H13Cl3N2OS
Asmaval
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Asmaval
fda sheet
Asmaval
msds (material safety sheet)
Asmaval
Synthesis Reference
No information avaliable
Asmaval
Molecular Weight
387.711 g/mol
Asmaval
Melting Point
No information avaliable
Asmaval
H2O Solubility
No information avaliable
Asmaval
State
Solid
Asmaval
LogP
4.971
Asmaval
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Asmaval
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Asmaval
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Asmaval
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Asmaval
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Asmaval
Patient Information
Asmaval
Organisms Affected
Yeast and other fungi