Calmorex
Brand names,
Calmorex
Analogs
Calmorex
Brand Names Mixture
Calmorex
Chemical_Formula
C16H13Cl3N2OS
Calmorex
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Calmorex
fda sheet
Calmorex
msds (material safety sheet)
Calmorex
Synthesis Reference
No information avaliable
Calmorex
Molecular Weight
387.711 g/mol
Calmorex
Melting Point
No information avaliable
Calmorex
H2O Solubility
No information avaliable
Calmorex
State
Solid
Calmorex
LogP
4.971
Calmorex
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Calmorex
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Calmorex
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Calmorex
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Calmorex
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Calmorex
Patient Information
Calmorex
Organisms Affected
Yeast and other fungi