Distaval
Brand names,
Distaval
Analogs
Distaval
Brand Names Mixture
Distaval
Chemical_Formula
C16H13Cl3N2OS
Distaval
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Distaval
fda sheet
Distaval
msds (material safety sheet)
Distaval
Synthesis Reference
No information avaliable
Distaval
Molecular Weight
387.711 g/mol
Distaval
Melting Point
No information avaliable
Distaval
H2O Solubility
No information avaliable
Distaval
State
Solid
Distaval
LogP
4.971
Distaval
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Distaval
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Distaval
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Distaval
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Distaval
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Distaval
Patient Information
Distaval
Organisms Affected
Yeast and other fungi