Gastrinide
Brand names,
Gastrinide
Analogs
Gastrinide
Brand Names Mixture
Gastrinide
Chemical_Formula
C16H13Cl3N2OS
Gastrinide
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Gastrinide
fda sheet
Gastrinide
msds (material safety sheet)
Gastrinide
Synthesis Reference
No information avaliable
Gastrinide
Molecular Weight
387.711 g/mol
Gastrinide
Melting Point
No information avaliable
Gastrinide
H2O Solubility
No information avaliable
Gastrinide
State
Solid
Gastrinide
LogP
4.971
Gastrinide
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Gastrinide
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Gastrinide
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Gastrinide
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Gastrinide
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Gastrinide
Patient Information
Gastrinide
Organisms Affected
Yeast and other fungi