Valgraine
Brand names,
Valgraine
Analogs
Valgraine
Brand Names Mixture
Valgraine
Chemical_Formula
C16H13Cl3N2OS
Valgraine
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Valgraine
fda sheet
Valgraine
msds (material safety sheet)
Valgraine
Synthesis Reference
No information avaliable
Valgraine
Molecular Weight
387.711 g/mol
Valgraine
Melting Point
No information avaliable
Valgraine
H2O Solubility
No information avaliable
Valgraine
State
Solid
Valgraine
LogP
4.971
Valgraine
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Valgraine
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Valgraine
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Valgraine
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Valgraine
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Valgraine
Patient Information
Valgraine
Organisms Affected
Yeast and other fungi