N-Phthalimidoglutamic acid imide
Brand names,
N-Phthalimidoglutamic acid imide
Analogs
N-Phthalimidoglutamic acid imide
Brand Names Mixture
N-Phthalimidoglutamic acid imide
Chemical_Formula
C16H13Cl3N2OS
N-Phthalimidoglutamic acid imide
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
N-Phthalimidoglutamic acid imide
fda sheet
N-Phthalimidoglutamic acid imide
msds (material safety sheet)
N-Phthalimidoglutamic acid imide
Synthesis Reference
No information avaliable
N-Phthalimidoglutamic acid imide
Molecular Weight
387.711 g/mol
N-Phthalimidoglutamic acid imide
Melting Point
No information avaliable
N-Phthalimidoglutamic acid imide
H2O Solubility
No information avaliable
N-Phthalimidoglutamic acid imide
State
Solid
N-Phthalimidoglutamic acid imide
LogP
4.971
N-Phthalimidoglutamic acid imide
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
N-Phthalimidoglutamic acid imide
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
N-Phthalimidoglutamic acid imide
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
N-Phthalimidoglutamic acid imide
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
N-Phthalimidoglutamic acid imide
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
N-Phthalimidoglutamic acid imide
Patient Information
N-Phthalimidoglutamic acid imide
Organisms Affected
Yeast and other fungi