Grippex
Brand names,
Grippex
Analogs
Grippex
Brand Names Mixture
Grippex
Chemical_Formula
C16H13Cl3N2OS
Grippex
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Grippex
fda sheet
Grippex
msds (material safety sheet)
Grippex
Synthesis Reference
No information avaliable
Grippex
Molecular Weight
387.711 g/mol
Grippex
Melting Point
No information avaliable
Grippex
H2O Solubility
No information avaliable
Grippex
State
Solid
Grippex
LogP
4.971
Grippex
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Grippex
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Grippex
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Grippex
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Grippex
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Grippex
Patient Information
Grippex
Organisms Affected
Yeast and other fungi