Ulcerfen
Brand names,
Ulcerfen
Analogs
Ulcerfen
Brand Names Mixture
Ulcerfen
Chemical_Formula
C10H16N6S
Ulcerfen
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Ulcerfen
fda sheet
Ulcerfen
msds (material safety sheet)
Ulcerfen
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Ulcerfen
Molecular Weight
252.34 g/mol
Ulcerfen
Melting Point
142 oC
Ulcerfen
H2O Solubility
0.5 g/100 mL
Ulcerfen
State
Solid
Ulcerfen
LogP
0.879
Ulcerfen
Dosage Forms
Tablets; Oral solution
Ulcerfen
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Ulcerfen
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Ulcerfen
Absorption
Rapid 60-70%
Ulcerfen
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Ulcerfen
Patient Information
Ulcerfen
Organisms Affected
Humans and other mammals