Imidene
Brand names,
Imidene
Analogs
Imidene
Brand Names Mixture
Imidene
Chemical_Formula
C16H13Cl3N2OS
Imidene
RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Imidene
fda sheet
Imidene
msds (material safety sheet)
Imidene
Synthesis Reference
No information avaliable
Imidene
Molecular Weight
387.711 g/mol
Imidene
Melting Point
No information avaliable
Imidene
H2O Solubility
No information avaliable
Imidene
State
Solid
Imidene
LogP
4.971
Imidene
Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Imidene
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Imidene
Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Imidene
Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Imidene
side effects and Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Imidene
Patient Information
Imidene
Organisms Affected
Yeast and other fungi