Categoria
Methylprednisolone, Pharma
Nombres de marca,
Methylprednisolone, Pharma
Analogos
Methylprednisolone, Pharma
Marca los nombres de mezcla
Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate) Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur) Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water) Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate) Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Methylprednisolone, Pharma
Formula quimica
C22H30O5
Methylprednisolone, Pharma
RX enlace
http://www.rxlist.com/cgi/generic/methprd.htm
Methylprednisolone, Pharma
FDA hoja
Methylprednisolone, Pharma
MSDS (hoja de seguridad de materiales)
Methylprednisolone, Pharma
Sintesis de referencia
Sebek, Spero, EE.UU. Pat. 2,897,218 (1959)
Methylprednisolone, Pharma
Peso molecular
374.471 g/mol
Methylprednisolone, Pharma
Punto de fusion
232.5 oC
Methylprednisolone, Pharma
H2O Solubilidad
120 mg / L
Methylprednisolone, Pharma
Estado
Solid
Methylprednisolone, Pharma
LogP
2.134
Methylprednisolone, Pharma
Formas de dosificacion
Tabletas, suspensión
Methylprednisolone, Pharma
Indicacion
La terapia adyuvante para administración a corto plazo en la artritis reumatoide.
Methylprednisolone, Pharma
Farmacologia
Metilprednisolona y sus derivados, succinato sódico de metilprednisolona y metilprednisolona, son glucocorticoides sintéticos utilizados como agentes antiinflamatorios o inmunosupresores.
Methylprednisolone, Pharma
Absorcion
La biodisponibilidad oral del 80-99%
Methylprednisolone, Pharma
Toxicidad
DL50 = 2000 mg / kg (por vía oral en ratas)
Methylprednisolone, Pharma
Informacion de Pacientes
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Methylprednisolone, Pharma
Organismos afectados
Humanos y otros mamíferos