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Promacortine Brand names, Promacortine Analogs

Promacortine Brand Names Mixture

  • Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
  • Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
  • Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
  • Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
  • Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)

Promacortine Chemical_Formula

C22H30O5

Promacortine RX_link

http://www.rxlist.com/cgi/generic/methprd.htm

Promacortine fda sheet

Promacortine FDA

Promacortine msds (material safety sheet)

Promacortine MSDS

Promacortine Synthesis Reference

Sebek, Spero, U.S. Pat. 2,897,218 (1959)

Promacortine Molecular Weight

374.471 g/mol

Promacortine Melting Point

232.5 oC

Promacortine H2O Solubility

120 mg/L

Promacortine State

Solid

Promacortine LogP

2.134

Promacortine Dosage Forms

Tablets; Suspension

Promacortine Indication

Adjunctive therapy for short-term administration in rheumatoid arthritis.

Promacortine Pharmacology

Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.

Promacortine Absorption

Oral bioavailability 80-99%

Promacortine side effects and Toxicity

LD50=2000 mg/kg (orally in rat)

Promacortine Patient Information

Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.

 

Promacortine Organisms Affected

Humans and other mammals