Moderin
Brand names,
Moderin
Analogs
Moderin
Brand Names Mixture
- Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
- Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
- Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
- Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
- Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Moderin
Chemical_Formula
C22H30O5
Moderin
RX_link
http://www.rxlist.com/cgi/generic/methprd.htm
Moderin
fda sheet
Moderin
msds (material safety sheet)
Moderin
Synthesis Reference
Sebek, Spero, U.S. Pat. 2,897,218 (1959)
Moderin
Molecular Weight
374.471 g/mol
Moderin
Melting Point
232.5 oC
Moderin
H2O Solubility
120 mg/L
Moderin
State
Solid
Moderin
LogP
2.134
Moderin
Dosage Forms
Tablets; Suspension
Moderin
Indication
Adjunctive therapy for short-term administration in rheumatoid arthritis.
Moderin
Pharmacology
Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.
Moderin
Absorption
Oral bioavailability 80-99%
Moderin
side effects and Toxicity
LD50=2000 mg/kg (orally in rat)
Moderin
Patient Information
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Moderin
Organisms Affected
Humans and other mammals