Dopomedrol
Brand names,
Dopomedrol
Analogs
Dopomedrol
Brand Names Mixture
- Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
- Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
- Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
- Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
- Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Dopomedrol
Chemical_Formula
C22H30O5
Dopomedrol
RX_link
http://www.rxlist.com/cgi/generic/methprd.htm
Dopomedrol
fda sheet
Dopomedrol
msds (material safety sheet)
Dopomedrol
Synthesis Reference
Sebek, Spero, U.S. Pat. 2,897,218 (1959)
Dopomedrol
Molecular Weight
374.471 g/mol
Dopomedrol
Melting Point
232.5 oC
Dopomedrol
H2O Solubility
120 mg/L
Dopomedrol
State
Solid
Dopomedrol
LogP
2.134
Dopomedrol
Dosage Forms
Tablets; Suspension
Dopomedrol
Indication
Adjunctive therapy for short-term administration in rheumatoid arthritis.
Dopomedrol
Pharmacology
Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.
Dopomedrol
Absorption
Oral bioavailability 80-99%
Dopomedrol
side effects and Toxicity
LD50=2000 mg/kg (orally in rat)
Dopomedrol
Patient Information
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Dopomedrol
Organisms Affected
Humans and other mammals