Methylprednisolonum [Inn-Latin] en es it fr

Methylprednisolonum [Inn-Latin] Brand names, Methylprednisolonum [Inn-Latin] Analogs

Methylprednisolonum [Inn-Latin] Brand Names Mixture

  • Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
  • Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
  • Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
  • Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
  • Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)

Methylprednisolonum [Inn-Latin] Chemical_Formula

C22H30O5

Methylprednisolonum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/methprd.htm

Methylprednisolonum [Inn-Latin] fda sheet

Methylprednisolonum_[Inn-Latin] FDA

Methylprednisolonum [Inn-Latin] msds (material safety sheet)

Methylprednisolonum_[Inn-Latin] MSDS

Methylprednisolonum [Inn-Latin] Synthesis Reference

Sebek, Spero, U.S. Pat. 2,897,218 (1959)

Methylprednisolonum [Inn-Latin] Molecular Weight

374.471 g/mol

Methylprednisolonum [Inn-Latin] Melting Point

232.5 oC

Methylprednisolonum [Inn-Latin] H2O Solubility

120 mg/L

Methylprednisolonum [Inn-Latin] State

Solid

Methylprednisolonum [Inn-Latin] LogP

2.134

Methylprednisolonum [Inn-Latin] Dosage Forms

Tablets; Suspension

Methylprednisolonum [Inn-Latin] Indication

Adjunctive therapy for short-term administration in rheumatoid arthritis.

Methylprednisolonum [Inn-Latin] Pharmacology

Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.

Methylprednisolonum [Inn-Latin] Absorption

Oral bioavailability 80-99%

Methylprednisolonum [Inn-Latin] side effects and Toxicity

LD50=2000 mg/kg (orally in rat)

Methylprednisolonum [Inn-Latin] Patient Information

Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.

 

Methylprednisolonum [Inn-Latin] Organisms Affected

Humans and other mammals