Reactenol
Brand names,
Reactenol
Analogs
Reactenol
Brand Names Mixture
- Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
- Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
- Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
- Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
- Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Reactenol
Chemical_Formula
C22H30O5
Reactenol
RX_link
http://www.rxlist.com/cgi/generic/methprd.htm
Reactenol
fda sheet
Reactenol
msds (material safety sheet)
Reactenol
Synthesis Reference
Sebek, Spero, U.S. Pat. 2,897,218 (1959)
Reactenol
Molecular Weight
374.471 g/mol
Reactenol
Melting Point
232.5 oC
Reactenol
H2O Solubility
120 mg/L
Reactenol
State
Solid
Reactenol
LogP
2.134
Reactenol
Dosage Forms
Tablets; Suspension
Reactenol
Indication
Adjunctive therapy for short-term administration in rheumatoid arthritis.
Reactenol
Pharmacology
Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.
Reactenol
Absorption
Oral bioavailability 80-99%
Reactenol
side effects and Toxicity
LD50=2000 mg/kg (orally in rat)
Reactenol
Patient Information
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Reactenol
Organisms Affected
Humans and other mammals