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MEPRDL Brand names, MEPRDL Analogs

MEPRDL Brand Names Mixture

  • Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
  • Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
  • Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
  • Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
  • Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)

MEPRDL Chemical_Formula

C22H30O5

MEPRDL RX_link

http://www.rxlist.com/cgi/generic/methprd.htm

MEPRDL fda sheet

MEPRDL FDA

MEPRDL msds (material safety sheet)

MEPRDL MSDS

MEPRDL Synthesis Reference

Sebek, Spero, U.S. Pat. 2,897,218 (1959)

MEPRDL Molecular Weight

374.471 g/mol

MEPRDL Melting Point

232.5 oC

MEPRDL H2O Solubility

120 mg/L

MEPRDL State

Solid

MEPRDL LogP

2.134

MEPRDL Dosage Forms

Tablets; Suspension

MEPRDL Indication

Adjunctive therapy for short-term administration in rheumatoid arthritis.

MEPRDL Pharmacology

Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.

MEPRDL Absorption

Oral bioavailability 80-99%

MEPRDL side effects and Toxicity

LD50=2000 mg/kg (orally in rat)

MEPRDL Patient Information

Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.

 

MEPRDL Organisms Affected

Humans and other mammals