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Nirypan Brand names, Nirypan Analogs

Nirypan Brand Names Mixture

  • Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
  • Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
  • Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
  • Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
  • Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)

Nirypan Chemical_Formula


Nirypan RX_link

Nirypan fda sheet

Nirypan FDA

Nirypan msds (material safety sheet)

Nirypan MSDS

Nirypan Synthesis Reference

Sebek, Spero, U.S. Pat. 2,897,218 (1959)

Nirypan Molecular Weight

374.471 g/mol

Nirypan Melting Point

232.5 oC

Nirypan H2O Solubility

120 mg/L

Nirypan State


Nirypan LogP


Nirypan Dosage Forms

Tablets; Suspension

Nirypan Indication

Adjunctive therapy for short-term administration in rheumatoid arthritis.

Nirypan Pharmacology

Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.

Nirypan Absorption

Oral bioavailability 80-99%

Nirypan side effects and Toxicity

LD50=2000 mg/kg (orally in rat)

Nirypan Patient Information

Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.


Nirypan Organisms Affected

Humans and other mammals