Medrol Adt Pak
Brand names,
Medrol Adt Pak
Analogs
Medrol Adt Pak
Brand Names Mixture
- Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
- Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
- Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
- Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
- Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Medrol Adt Pak
Chemical_Formula
C22H30O5
Medrol Adt Pak
RX_link
http://www.rxlist.com/cgi/generic/methprd.htm
Medrol Adt Pak
fda sheet
Medrol Adt Pak
msds (material safety sheet)
Medrol Adt Pak
Synthesis Reference
Sebek, Spero, U.S. Pat. 2,897,218 (1959)
Medrol Adt Pak
Molecular Weight
374.471 g/mol
Medrol Adt Pak
Melting Point
232.5 oC
Medrol Adt Pak
H2O Solubility
120 mg/L
Medrol Adt Pak
State
Solid
Medrol Adt Pak
LogP
2.134
Medrol Adt Pak
Dosage Forms
Tablets; Suspension
Medrol Adt Pak
Indication
Adjunctive therapy for short-term administration in rheumatoid arthritis.
Medrol Adt Pak
Pharmacology
Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.
Medrol Adt Pak
Absorption
Oral bioavailability 80-99%
Medrol Adt Pak
side effects and Toxicity
LD50=2000 mg/kg (orally in rat)
Medrol Adt Pak
Patient Information
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Medrol Adt Pak
Organisms Affected
Humans and other mammals