Noretona
Brand names,
Noretona
Analogs
Noretona
Brand Names Mixture
- Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
- Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
- Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
- Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
- Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Noretona
Chemical_Formula
C22H30O5
Noretona
RX_link
http://www.rxlist.com/cgi/generic/methprd.htm
Noretona
fda sheet
Noretona
msds (material safety sheet)
Noretona
Synthesis Reference
Sebek, Spero, U.S. Pat. 2,897,218 (1959)
Noretona
Molecular Weight
374.471 g/mol
Noretona
Melting Point
232.5 oC
Noretona
H2O Solubility
120 mg/L
Noretona
State
Solid
Noretona
LogP
2.134
Noretona
Dosage Forms
Tablets; Suspension
Noretona
Indication
Adjunctive therapy for short-term administration in rheumatoid arthritis.
Noretona
Pharmacology
Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.
Noretona
Absorption
Oral bioavailability 80-99%
Noretona
side effects and Toxicity
LD50=2000 mg/kg (orally in rat)
Noretona
Patient Information
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Noretona
Organisms Affected
Humans and other mammals