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Esametone Brand names, Esametone Analogs

Esametone Brand Names Mixture

  • Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
  • Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
  • Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
  • Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
  • Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)

Esametone Chemical_Formula


Esametone RX_link

Esametone fda sheet

Esametone FDA

Esametone msds (material safety sheet)

Esametone MSDS

Esametone Synthesis Reference

Sebek, Spero, U.S. Pat. 2,897,218 (1959)

Esametone Molecular Weight

374.471 g/mol

Esametone Melting Point

232.5 oC

Esametone H2O Solubility

120 mg/L

Esametone State


Esametone LogP


Esametone Dosage Forms

Tablets; Suspension

Esametone Indication

Adjunctive therapy for short-term administration in rheumatoid arthritis.

Esametone Pharmacology

Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.

Esametone Absorption

Oral bioavailability 80-99%

Esametone side effects and Toxicity

LD50=2000 mg/kg (orally in rat)

Esametone Patient Information

Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.


Esametone Organisms Affected

Humans and other mammals