Urbasone
Brand names,
Urbasone
Analogs
Urbasone
Brand Names Mixture
- Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
- Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
- Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
- Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
- Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Urbasone
Chemical_Formula
C22H30O5
Urbasone
RX_link
http://www.rxlist.com/cgi/generic/methprd.htm
Urbasone
fda sheet
Urbasone
msds (material safety sheet)
Urbasone
Synthesis Reference
Sebek, Spero, U.S. Pat. 2,897,218 (1959)
Urbasone
Molecular Weight
374.471 g/mol
Urbasone
Melting Point
232.5 oC
Urbasone
H2O Solubility
120 mg/L
Urbasone
State
Solid
Urbasone
LogP
2.134
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Dosage Forms
Tablets; Suspension
Urbasone
Indication
Adjunctive therapy for short-term administration in rheumatoid arthritis.
Urbasone
Pharmacology
Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.
Urbasone
Absorption
Oral bioavailability 80-99%
Urbasone
side effects and Toxicity
LD50=2000 mg/kg (orally in rat)
Urbasone
Patient Information
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Urbasone
Organisms Affected
Humans and other mammals