Medrol Dosepak
Brand names,
Medrol Dosepak
Analogs
Medrol Dosepak
Brand Names Mixture
- Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
- Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
- Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
- Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
- Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Medrol Dosepak
Chemical_Formula
C22H30O5
Medrol Dosepak
RX_link
http://www.rxlist.com/cgi/generic/methprd.htm
Medrol Dosepak
fda sheet
Medrol Dosepak
msds (material safety sheet)
Medrol Dosepak
Synthesis Reference
Sebek, Spero, U.S. Pat. 2,897,218 (1959)
Medrol Dosepak
Molecular Weight
374.471 g/mol
Medrol Dosepak
Melting Point
232.5 oC
Medrol Dosepak
H2O Solubility
120 mg/L
Medrol Dosepak
State
Solid
Medrol Dosepak
LogP
2.134
Medrol Dosepak
Dosage Forms
Tablets; Suspension
Medrol Dosepak
Indication
Adjunctive therapy for short-term administration in rheumatoid arthritis.
Medrol Dosepak
Pharmacology
Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.
Medrol Dosepak
Absorption
Oral bioavailability 80-99%
Medrol Dosepak
side effects and Toxicity
LD50=2000 mg/kg (orally in rat)
Medrol Dosepak
Patient Information
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Medrol Dosepak
Organisms Affected
Humans and other mammals