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Penicillamine Brand names, Penicillamine Analogs

Penicillamine Brand Names Mixture

  • No information avaliable

Penicillamine Chemical_Formula

C5H11NO2S

Penicillamine RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

Penicillamine fda sheet

Penicillamine FDA

Penicillamine msds (material safety sheet)

Penicillamine MSDS

Penicillamine Synthesis Reference

No information avaliable

Penicillamine Molecular Weight

149.212 g/mol

Penicillamine Melting Point

198.5 oC

Penicillamine H2O Solubility

1.11E+005 mg/L

Penicillamine State

Solid

Penicillamine LogP

-2.09

Penicillamine Dosage Forms

Capsule; Tablet

Penicillamine Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

Penicillamine Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

Penicillamine Absorption

rapidly but incompletely

Penicillamine side effects and Toxicity

No information avaliable

Penicillamine Patient Information

No information avaliable

Penicillamine Organisms Affected

Humans and other mammals