Depen
Depen Brand names, Depen Analogs
- Artamine
- Cuprenil
- Cuprimine
- Cupripen
- D-Mercaptovaline
- D-Penamine
- D-Penicilamine
- D-Penicillamine
- D-Penicyllamine
- DPA
- Depamine
- Depen
- Dimethylcysteine
- Distamine
- Emtexate
- HiFD`JxPBLbdTljjZDp@
- Kuprenil
- L-Penicillamine
- L-Penicillamine 99.5+
- Mercaptovaline
- Mercaptyl
- Metalcaptase
- PCA
- Pendramine
- Penicilamina [INN-Spanish]
- Penicillamin
- Penicillamina [DCIT]
- Penicillamine [USAN:BAN:INN:JAN]
- Penicillaminum [INN-Latin]
- Penicilllamine
- Perdolat
- Reduced D-penicillamine
- Reduced penicillamine
- Sufirtan
- Trolovol
- beta,beta-Dimethylcysteine
- beta-Thiovaline
Depen Brand Names Mixture
- No information avaliable
Depen Chemical_Formula
C5H11NO2S
Depen RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Depen fda sheet
Depen msds (material safety sheet)
Depen Synthesis Reference
No information avaliable
Depen Molecular Weight
149.212 g/mol
Depen Melting Point
198.5 oC
Depen H2O Solubility
1.11E+005 mg/L
Depen State
Solid
Depen LogP
-2.09
Depen Dosage Forms
Capsule; Tablet
Depen Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Depen Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Depen Absorption
rapidly but incompletely
Depen side effects and Toxicity
No information avaliable
Depen Patient Information
No information avaliable
Depen Organisms Affected
Humans and other mammals
