Pendramine en es it fr

Pendramine Brand names, Pendramine Analogs

Pendramine Brand Names Mixture

  • No information avaliable

Pendramine Chemical_Formula


Pendramine RX_link

Pendramine fda sheet

Pendramine FDA

Pendramine msds (material safety sheet)

Pendramine MSDS

Pendramine Synthesis Reference

No information avaliable

Pendramine Molecular Weight

149.212 g/mol

Pendramine Melting Point

198.5 oC

Pendramine H2O Solubility

1.11E+005 mg/L

Pendramine State


Pendramine LogP


Pendramine Dosage Forms

Capsule; Tablet

Pendramine Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

Pendramine Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

Pendramine Absorption

rapidly but incompletely

Pendramine side effects and Toxicity

No information avaliable

Pendramine Patient Information

No information avaliable

Pendramine Organisms Affected

Humans and other mammals