L-Penicillamine en es it fr

L-Penicillamine Brand names, L-Penicillamine Analogs

L-Penicillamine Brand Names Mixture

  • No information avaliable

L-Penicillamine Chemical_Formula

C5H11NO2S

L-Penicillamine RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

L-Penicillamine fda sheet

L-Penicillamine FDA

L-Penicillamine msds (material safety sheet)

L-Penicillamine MSDS

L-Penicillamine Synthesis Reference

No information avaliable

L-Penicillamine Molecular Weight

149.212 g/mol

L-Penicillamine Melting Point

198.5 oC

L-Penicillamine H2O Solubility

1.11E+005 mg/L

L-Penicillamine State

Solid

L-Penicillamine LogP

-2.09

L-Penicillamine Dosage Forms

Capsule; Tablet

L-Penicillamine Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

L-Penicillamine Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

L-Penicillamine Absorption

rapidly but incompletely

L-Penicillamine side effects and Toxicity

No information avaliable

L-Penicillamine Patient Information

No information avaliable

L-Penicillamine Organisms Affected

Humans and other mammals