D-Penicilamine en es it fr

D-Penicilamine Brand names, D-Penicilamine Analogs

D-Penicilamine Brand Names Mixture

  • No information avaliable

D-Penicilamine Chemical_Formula

C5H11NO2S

D-Penicilamine RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

D-Penicilamine fda sheet

D-Penicilamine FDA

D-Penicilamine msds (material safety sheet)

D-Penicilamine MSDS

D-Penicilamine Synthesis Reference

No information avaliable

D-Penicilamine Molecular Weight

149.212 g/mol

D-Penicilamine Melting Point

198.5 oC

D-Penicilamine H2O Solubility

1.11E+005 mg/L

D-Penicilamine State

Solid

D-Penicilamine LogP

-2.09

D-Penicilamine Dosage Forms

Capsule; Tablet

D-Penicilamine Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

D-Penicilamine Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

D-Penicilamine Absorption

rapidly but incompletely

D-Penicilamine side effects and Toxicity

No information avaliable

D-Penicilamine Patient Information

No information avaliable

D-Penicilamine Organisms Affected

Humans and other mammals