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PCA Brand names, PCA Analogs

PCA Brand Names Mixture

  • No information avaliable

PCA Chemical_Formula

C5H11NO2S

PCA RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

PCA fda sheet

PCA FDA

PCA msds (material safety sheet)

PCA MSDS

PCA Synthesis Reference

No information avaliable

PCA Molecular Weight

149.212 g/mol

PCA Melting Point

198.5 oC

PCA H2O Solubility

1.11E+005 mg/L

PCA State

Solid

PCA LogP

-2.09

PCA Dosage Forms

Capsule; Tablet

PCA Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

PCA Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

PCA Absorption

rapidly but incompletely

PCA side effects and Toxicity

No information avaliable

PCA Patient Information

No information avaliable

PCA Organisms Affected

Humans and other mammals