C5H11NO2S
http://www.rxlist.com/cgi/generic3/penicillamine.htm
No information avaliable
149.212 g/mol
198.5 oC
1.11E+005 mg/L
Solid
-2.09
Capsule; Tablet
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
rapidly but incompletely
No information avaliable
No information avaliable
Humans and other mammals